UTIs, Yeast Infections, and Antibiotics

September 24th, 2009

Why do you get a yeast infection after you get treated with antibiotics for a UTI?

The mainstay of treatment for an acute urinary tract infection is antibiotics plus lots and lots of fluid and anything with proanthocyanidins.

Like we have explained in other blogs, the most common cause of urinary tract infection is the little bugger, e. coli.  Usually, patients are prescribed a course of Cipro, or another antibiotic to kill the bugs in your urinary tract.

Bacteria aren’t always bad.  In your urinary tract, most bacteria are bad, but in the vagina, there are some good bacteria that battle yeast.  When you take antibiotics to kill off the bacteria in your urinary tract, it also kills some of the good bacteria in your vagina, thereby disturbing the normal balance.  According to Dr. Spock, “Anywhere from 25 to -70 percent of women will get a yeast infection after taking a course of antibiotics.”  The good bacteria die and the yeast then have the opportunity to thrive.

Can you prevent a yeast infection when you are taking antibiotics?

Sometimes.  Yeast thrive in wet, warm environments.  Cotton undies help to absorb some of the moisture and make the environment less conducive to yeast growth.  Better yet, when you go to sleep, go commando.  Wearing no underwear keeps the vaginal area dry, which also helps.  Lastly, keep the area clean.  Practice good hygiene- shower and take baths, but do not douche.  Douches can sometimes make things worse.

So, ladies, try not to get a UTI.  Not only can you get the consequences of a UTI, you also get the side effects of antibiotics!

MIT 100K Business Plan Competition: Lessons Learned From Finalists

September 16th, 2009

AH MIT100K 2

Backstage @ the MIT 100K Entreprenuership Competition Finals: Tina and I felt kind of like the Hickory High School team in the locker room. Remember? From the movie Hoosiers? (check out the clip for goosebumps) We won the Products & Services Track. We were honored and humbled to be Finalists:

 

 So what made us successful?

1. Round Peg in Round Hole: We weren’t faking it. Our team clearly believed in YouTea! and were the right team to execute the plan. Judges noted our authentic passion for our product, women’s health and entrepreneurship. We certainly noticed that about all of the finalists: K Splice, MeterLive, Global Cycle Solutions etc.

2. We Feel Your Pain . . . And Might Be Able To Help You: We identified a problem (urinary tract infections). Women were not satisfied with current solutions (lots of calories, lots of sugar, lots of acidity, not optimized for women’s health). We developed a solution (YouTea!). The problem came first, we listened to the customer, and developed the solution. Not the other way around.

3. We Listened To Our Mentors . . . But Never Lost Our Soul: We were lucky to have fantastic mentors in nutritional medicine, venture capital, marketing, and food and beverage industry who taught us a ton about how to develop a successful business plan. Still, we were committed to reinventing the rules of urinary health and women’s health. That means that not every YouTea! strategy is “business as usual.” For instance, some suggested that we use artificial sweetener. But we are dedicated to making YouTea! all natural. It may take a little longer, and cost a little more, but we are committed to delivering an all-natural product.

4. We Had A Real Product: The majority of business plan entrants have great concepts, great powerpoints, great resumes, great financial projections . . . but nothing that you can hold. We used our $1000 budget to develop a prototype. Nothing special, but a working sample of what YouTea! will be like on the shelves.

So what could we have done better?

1. Product Or A Business? YouTea! will develop a women’s health functional beverage product line for many indications. In the future. For now, we are focused on urinary health. Some judges felt we were too focused, noting that it is difficult for a 1 product company to survive in a retail environment. I’ll take the hit for that decision. I’ve always believed in focus. Call it my Army experience. I have that poster on my wall (not really).

2. Wow Factor We weren’t building a rocketship. Just a functional beverage. This is an MIT competition after all, and super cool technology gets people excited. Then again, if Tina and I tried to build a rocketship, it would probably look like this.

Sex and Urinary Tract Infections

September 5th, 2009

Another day in the Emergency Department, more urinary tract infections.

It’s a question that I get asked all the time:  Why does sex cause urinary tract infections?

Well, sex in and of itself does not cause UTI’s, per se.  Bacteria in the urinary tract cause UTI.

Let’s go through some definitions first.

  • UTI: Urinary tract infection, some also refer to it as a bladder infection
  • Urinary tract: kidneys, ureter, bladder
  • E.Coli: Escherichia coli, bacteria that causes 90% of UTIs.  It also causes meningitis, pneumonia, food poisoning and other bad illnesses.  E.Coli are bacteria normally found in your large intestines and everyone has it in their bodies.  E.Coli is in everyone’s fecal matter.
  • Urethra: the opening through which urine leaves the body. The opening is right below the clitoris.

Sex is associated with UTIs because placing anything near your urethra is going to increase your chance of getting a UTI.  Similarly, wearing tight underwear (thongs) or synthetic underwear (nylon, silk) is also going to increase the chance of getting a UTI.

Simply stated, when you have sex, sometimes you get a tiny amount of fecal matter near your urethra.  E.coli are very smart and they climb into your urethra and crawl up your urethra, up into your bladder.  That’s when the UTI begins.  E.Coli multiply like rabbits in your bladder and then you feel the pain, need to urinate, and bladder spasms.  If you don’t get it treated, it can up to your kidneys and then you get a kidney infection (pyelonephritis), then the bacteria can get into your bloodstream and causes urosepsis (bacteria in your blood from a urinary source), and death.

Most of the time however, you get a UTI, you get treated, and it will not be complicated.  In fact, according to iVillage: “In young healthy women, the vast majority of urinary infections are mild. More than 80 percent actually resolve without any treatment. However, I recommend seeking treatment in all suspected cases of urinary tract infections, to avoid the rare risk of serious complications.”

Hope that answers your question.

A Type Proanthocyanidins: Redefining Urinary Health, Redefining Marketing

September 2nd, 2009

AH BH

One of the many reasons that Tina and I founded YouTea! together lay in our mutual desire to be creative. We did not believe that pharmaceutical and biotech companies should have a monopoly on women’s health solutions. And we did not believe that the pain relief products on the market are proper solutions for urinary health. They are merely band aids that mask symptoms, they are not optimized women’s health solutions. YouTea! rests on a foundation of providing creative solutions for women’s health and urinary health.

So now I have our first dilemma, where our mission and “tried and true” marketing tactics are not quite aligned. I am no marketing expert, just a dude with an MBA, a vision, a goal, and several pairs of Old Navy cargo pants. So I need help from professional marketers. I spend several hours a day speaking with marketing experts and consultants and much of their advice is valuable. However, many want to simplify YouTea!’s vision, and I am just not so sure . . .

Case in point: A Type Proanthocyanidins. What are proanthocyanidins? They are powerful antioxidants, found in a host of foods such as grapes, red wine and many types of berries. One of the many benefits of proanthocyanidins is that they bind to E. coli. A-Type proanthocyanidins are better at binding to bacteria than other types[1]. What does this matter for YouTea!? Studies demonstrate that 80-90% of urinary tract infections are caused by E. coli[2]. E. coli cause urinary tract infections because they bind to the urinary tract and release toxins. A Type proanthocyanidins bind to E. coli, thereby preventing the bacteria from attaching to the urinary tract.

This seems like a simple concept: proanthocyanidins are good because they bind to the bacteria that cause UTIs. So proanthocyanidins are our friends, our heroic promoters of urinary tract health. Right? Right?

“Not necessarily!” say the marketers, wagging their well-manicured fingers in my face:

“It’s such a complicated word.”

“7 syllables in 1 word!”

“Doesn’t exactly roll off the tongue”

“Consumers like simple words: Coke. Pepsi. Nike. Mac.”

“Why not just say supercalifragalisticexpeolidocious (idiot)?”

Some creative suggestions have been made. “Let’s simplify proanthocyanidins to (wait for it) . . .  PACs.” Woohoo. Too bad it rhymes with one of the most heinous words in the English language: “tax.”

So what do you think?!? Can we say “forget the old school, let’s rewrite the rules” and learn to say “proanthocyanidins” together? Or is the first of many lessons I have to learn about the conflict between idealism and feasibility?

 


[1] http://bit.ly/SWBSl

[2] http://bit.ly/hfMYb

Answers in the bathroom

August 29th, 2009
What I feel like sometimes.

What I feel like sometimes.

If you could see medical students and residents behind the scenes, it really is a scene out of “Scrubs,” the TV show.  Patients often give me their history and I go straight to the closet or the bathroom to go look up on my iphone or in a book how what I’m supposed to do.  When I catch myself doing it, it’s somewhat amusing.  Luckily I have my textbooks to guide what I’m supposed to do with 80% of the patients who are not complicated.

If only there were a women’s health beverage company playbook that was based on evidence and best practices.  Unfortunately, we there’s no formula for what people’s palates will like, no googlemaps for packaging, no recipe for magic marketing.

Too bad Alex and I can’t hide in the bathroom or closet sometimes and come out with the right answers.  That’d be nice.

Medicine is hard. Entrepreneurship is harder.

August 29th, 2009

Today was a rough day.  It started great and ended not so great.  Medicine is a tough field.  I’m never smart enough, I can’t work hard enough, I can’t help enough people.  But, thankfully, no one ever said medicine was easy and this is what I signed up for.  I signed up for the challenge, because I’m intellectually curious, because I care.  I really do care.

People work for years to become a doctor.  Four years of medical school costing $155,000 (on average).  Three to nine years of residency making $40,000 (on average).  And, it’s a beat down sometimes.  At the end of the day, it really does help people in dire need of medical attention, and it’s a safe path.

Medicine is hard.  Entrepreneurship is harder.

Entrepreneurs wake up every day believing that it will all be worth it in the end.  There are days, weeks, and maybe months of bad news, obstacles, and mind teasers.  We believe that we have a solution that is better or different than everyone else’s.  It’s audacious.  It’s courageous.  It’s absurd.  It’s exciting.  It’s hard.  It’s really really hard.

But, like medicine, if you make it through and work hard at it.  It’s worth it in the end.  It’s just that the end is more difficult to see sometimes in entrepreneurship.  And it’s risky.  To all those who are doing entrepreneurial ventures, especially in this economic environment, we are honored to join your club.  Cheers to success.  Cheers to hard work.  Cheers to some luck along the way.

Entrepreneurship in a downturn: Inspiration from the Bolt Bus

August 25th, 2009

AH BH

We recently celebrated the 10th anniversary of Woodstock ’99. Remember, that disastrously-planned festival after which the planners held up their hands and exclaimed “Water? Toilets? Shade? Oops! We forgot . . . “ (I think some of those people later got jobs in Army logistics by the way). Well, (in my best grandpa voice), I actually went to Woodstock ’99. And survived. Survived the mayhem. The mosh pits. The madness. Actually, I ended up spending about twice as much time on buses than at the actual concert. I was doing summer Army training at Fort Bragg in NC, and decided on a whim to “hop” on a bus and join my friends at Woodstock over the weekend. 18 hours after that “hop,” I sprinted off the Greyhound in Rome, NY having attracted every 400 lb gentleman who did not appreciate the importance of personal hygiene to sit right next to me on the various buses throughout our 6 state tour. After rocking out to Limp Bizkit, Kid Rock and Korn, I dragged myself back onto the Greyhound to return to NC, wishing that I could invent a teleporter. This time I was fortunate to sit next to a friendly fellow with “H-A-T-E” tattooed across his fingers.

When I finally emerged from that bus in NC, I kissed the ground and thanked the higher power for keeping me alive and made an important promise. I vowed never to ride a bus for longer than 3 hours again in my life. Never. I’ll take trains, water taxis, rent cars, hitchhike, bike, jog whatever it takes to avoid the horror of 18 hours on a bus without AC after someone relieves himself and then decides to share the details of his upcoming arraignment.

Well, I broke my promise last week. I had to travel to visited several vendors and manufacturers. And, as a start-up redefining the term “bootstrap,” I had no choice but to take the bus. $30 round trip. I dreaded the experience for weeks. I could only imagine whom I was going to attract. The 400 pounder or the hate metal enthusiast? Or maybe someone new awaited me? Soon I learned that, in the past 10 years, some enterprising entrepreneurs have redefined bus travel. AC. Comfortable seats. Wi-Fi! A driver who enforced the rules. And I was sitting next to a diminutive and smiling 100 lb. woman. Things were looking up.

My positive experience on the Bolt Bus made me optimistic about entrepreneurship in a downturn. We all know that there is not much capital available except for super-experienced entrepreneurs. But what Tina and I lack in experience we make up for in passion and grit. We are committed to improving women’s health. Changing the rules of urinary health. Providing women with an optimized solution.

So how does a downturn benefit us? We believe in YouTea! We are willing to sacrifice for YouTea! We don’t vacillate. We don’t take our football and go home at the first sign of adversity. We’ve had people (all dudes) tell us that they don’t “get” YouTea! “Why would women want an alternative?” they ask. We dust ourselves off and move on to the next one. We don’t seek the comfort of a big company to save us from adversity. It would be easy to say “well, it’s just impossible to start a company in this environment. We’re going to work at Microsoft.” And others will do that. Take their good ideas and bury them. Exit the marketplace. But we will wait out the storm, optimizing our product, gaining customer input to make sure YouTea! fills customer needs, and building buzz around our women’s health solution.

At the end of the day, we will be a better company and a better management team for being resilient during tough times. 10 years from now it will have been obvious – “Of course YouTea! was a good idea! They reinvented women’s health! Why didn’t I think of that?” Just like I got off the Bolt Bus the other day and said “Reinventing the bus ride? Why didn’t I think of that!?” It seems obvious to me now that a comfortable bus ride was in fact possible – it only took a few enterprising and passionate entrepreneurs to make it happen.

Take control.

August 21st, 2009

I had a patient last week who was arrested for wreckless endangerment of her 5 year old child.  She wouldn’t go into the details as to why she was arrested, but she had to spend 3 years in jail for what she had done.  Given her hospitalization was due to a relapse of her cocaine and heroin addiction, I’m guessing that the police decided that drugs and kids do not make for a good combination.

I sometimes struggle to help people who purposefully hurt others and helping people who won’t help themselves.  My 700lb patient has skin infections everywhere because he can’t bath himself properly.  The patient with lung cancer down the hall still smokes through his trachea hole in his neck.   My 50YO stroke patient who has a blood pressure of 200/120 refuses to take blood pressure medication, even though he might die within a couple of years.  I treat these patients like all of my other patients, but inside, I wish they could take control of their own health.

This is part of the reason why I am passionate about a solution for women’s health for women who actually care about their health. It may be a small step, helping to prevent UTIs, osteoporosis, or neural tube defects, but at least I know that the women who use our product care about their own health and wellness.  They are willing to take responsibility for their body.  Thank you for caring.  It makes my job easier.

How I rediscovered my entrepreneurial soul in a sweet potato pie

August 17th, 2009

AH BH

As an army officer, I never watched war movies or tv shows. Never. When someone would want my opinion on Blackhawk Down or We Were Soldiers, I would say “sorry dude, I missed it. I went to see Hitch.” It’s not that I was traumatized. I just lived the Army 24/7 and used my free time to escape from my career.

The same logic applied when I learned about the new show “Shark Tank,” in which entrepreneurs pitch their ideas to angel investors. “No way I’m watching that,” I thought to myself. “I live entrepreneurship 24/7, the LAST thing I want to do on a Sunday night is get my blood pumping over unfair valuations or un-scalable business models.” Unfortunately Brenda did not quite understand my sentiment. “Isn’t there an episode of Deadliest Catch or MythBusters on?” I implored. No way. She wanted to watch Shark Tank. And after hundreds of hours I have subjected her to Patriots pre-game shows, Patriots post-game shows, interviews with Patriots players, talk shows during which they talk about interviews with Patriots players, and oh yeah Patriots games (not even mentioning the Sox and Celtics), this was the least that I could do.

I decided to iron all of my clothes for the week while Brenda watched Shark Tank (yes I iron my clothes for the week on Sundays). Why was I so against this show? Thoughts of YouTea! speed through my head 24/7. Sometimes it’s good (like when the latest prototype comes in and tastes great) sometimes it’s bad (like when some dude investor insist that “he doesn’t understand the market need”) sometimes it’s great (when doctors and women insist that “they do, really, understand the market need”). Sunday night is a refuge. No good, bad, or great. No evaluating package designs. No debating investment terms. No negotiating with manufacturers. Just some time to chillax and forget about the business for a little while. 

Then Todd Wilson and his sweet potato pies entered into my life. Todd had turned a family recipe for sweet potato pies into a local retail and wholesale business. He grew too quickly and squandered his working capital. Rather than giving up and going to work for a commercial bakery, he dusted off his apron and strapped on his oven mitts a little tighter. As he told the audience of angels “he got his MBA in the streets, slept in my car for four months, regrouped and is back at it again.” Todd didn’t have a hell of a lot going for him – no real barriers to entry, no supply chain infrastructure, no high-profile investors or management team. But he had his family recipe and he had a hell of a lot of chutzpah. He knew his customer, and, to quote my man Emeril Lagasse “It’s a food of love thing.”

After two minutes of Todd Wilson I forgot about chillaxing. If this guy can get so excited about his pies, I better be excited about YouTea! No proanthocyanidins in sweet potato pie. No vitamins and antioxidants. Regular use of sweet potato pie is not going to promote women’s health or help prevent any urinary health problems. But YouTea! will.

Another 45 minutes of Shark Tank and I realize that the producers subscribe to the American Idol theory of presenting either really good or really bad performers. One entrepreneur, with some sort of surgically-implanted Bluetooth device, would make William Hung and his “she bangs” performance look professional. But I’ll never forget Todd Wilson and his dream of being THE sweet potato pie guy. I drop the iron and ask Brenda “where are those packaging designs?”

How did an Army infantry dude become a women’s health entrepreneur?

August 9th, 2009

AH BH

People have some strange reactions when they learn I am starting a women’s health venture:
“Why do you care about women’s health?!?”

Let us retrace our steps . . .
December 2005: Hitting 85 on the highway out of Fort Drum, NY. After 5.5 yearsI am leaving the Army. I know that one day I will look back upon my time in the Army fondly . . . trying not to look cold in front of my soldiers in -10 degrees, when they all knew I was cold and I knew that they knew I was cold . . . endless training sessions in Korea within earshot of the DMZ . . . leading 35 soldiers and 35 cases of dysentery throughout Kirkuk, Mosul and the backroads of northern Iraq . . . trying not to look hot in 120 degrees with 50 pounds of gear when, once again, my soldiers know I’m hot . . . drinking gallons of coffee as I tried to get food, water, ammunition and fuel to 700 soldiers in Baghdad. ONE DAY I will miss that. At that time I just wanted to get to Bowie, MD to see Brenda, my beautiful and amazing girlfriend.

June 2006: Not sure what to do with my life, I somehow end up as a supply chain management consultant. What does that mean? At this moment, it’s 3:30 am and I’m sprinting through a warehouse with a palm pilot and a clipboard trying to keep up with a forklift. Why? I’m still not quite sure, but I think it’s a ploy to give the other forklift drivers jokes for weeks. “You see that idiot in the collared shirt sprinting with the clipboard?” I get off work and randomly decide to call my buddy Will, who was wounded in Baghdad. “Turns out I get to keep my leg, there’s a new technology that allowed my leg to fuse together.” BINGO! AHA! I know what I want to do – New career choice: healthcare. Unfortunately healthcare companies won’t consider me until I get some new initials . . . PhD? Too long. MD? Yeah right . . . how about MBA? Just right.

July 2008: Sitting in a conference room at Medtronic during my summer internship, learning about new products, drifting off into thinking about running around Lake of the Isles that night . . . “25 Million women suffer from urinary incontinence” . . . “Excuse me,” I interrupt, “did you just say 25 Million women are incontinent?” “Yes” the product manager responds. 25 Million! This is shocking! Does 60 Minutes know? Katie Couric? Larry King? How could 1 out of every 3 women in the US suffer from this and NO ONE KNOWS EXCEPT THOSE THAT SUFFER?!?

November 2008: Sitting in a small room with lots of whiteboards at HBS. I’ve had enough. I’ve dug into other women’s health issues . . . chronic pain, treatment-resistant depression, osteoporosis. Talk about an under-served market. There are 30 billion cardiovascular products out there but the best they can do for incontinence are plugs and sling surgeries? Time to fix this. I’ve assembled a team of women’s health experts. Tina, someone I’ve grown to like and admire greatly, pipes up “well, classmates come to me all the time about UTIs. And the only real options are cranberry juice and antibiotics.” I’ve read about the problems with antibiotics . . . super-bugs, expensive, not to mention the hassle of seeing a doctor if you can get an appointment and if they let you go to it. I remember my wife unwillingly guzzling gallons of cranberry juice and having to skip dessert because of the sugar in cranberry juice. “Do cranberries really work?” I ask Tina . . . and that’s when I learned about proanthocyanidins, and that’s when I fell in love with YouTea! and that’s why this Army dude is working 18 hour days . . . to provide a new women’s health solution.